






You deserve
to feel better.
Change starts here.
Science-backed ketamine therapy to help you re-center and move forward.
Negative thoughts and emotions can turn your mental landscape into a maze of noise, doubt, and disconnection.
You don’t need another coping strategy that numbs or distracts.
You need a real shift.
Mindscape makes change possible.
Based in neuroscience, ketamine therapy can help interrupt the thought patterns behind anxiety and depression. It offers both fast relief and transformative, long-lasting benefits.
Our unique, flexible approach to at-home treatment goes beyond symptom relief, helping you turn ketamine insights into real-world breakthroughs.
Mindscape’s licensed clinical and pharmacy partners provide safe, personalized ketamine therapy at home.
Customized, precision doses offer deeply therapeutic experiences that align with your unique process. You stay connected every step of the way.
It’s your journey.
With Mindscape’s unique protocol, personalized support, and intuitive tools, you can find your way out of the maze and back to yourself.
Individual results vary. Ketamine therapy is not appropriate for everyone.
Important Safety Information
Mindscape connects individuals with licensed clinicians trained to diagnose and treat anxiety, depression, and other mental health conditions. If, after a clinical assessment, a licensed clinician determines ketamine to be an appropriate treatment, they may prescribe compounded ketamine troches (oral administration) or nasal sprays, produced by pharmacies under Section 503A of the federal Food, Drug, and Cosmetic Act (FDCA). Compounded drugs under Section 503A do not require FDA approval, and as such, the FDA has not verified the safety or effectiveness of the compounded ketamine for treating anxiety, depression, or other mental health issues. However, scientific literature supports the use of ketamine for these conditions.
Potential Side Effects
Ketamine may cause serious side effects, including but not limited to sedation, dissociation, and psychiatric events or worsening of mental health conditions, including schizophrenia, severe personality disorders, and other severe psychiatric disorders. Other risks include dependence, abuse, anxiety; increased blood pressure or heart rate; respiratory depression (a condition causing breathing to become slower and shallower and preventing the lungs from exchanging carbon dioxide and oxygen efficiently); urinary tract and bladder issues, such as urinary pain or incontinence, blood in urine, or reduced bladder size; altered time perception; dry mouth; elevated intraocular/intracranial pressure; loss of appetite; confusion, nausea/vomiting; blurred vision; and slurred speech.
The FDA has advised that at-home ketamine administration may present additional risks due to the absence of onsite healthcare providers to monitor for sedation or dissociative side effects.
Mindscape protocols and guidance are designed to minimize the risk of side effects or adverse events, and should be carefully followed. Ketamine should only be taken as directed by your treating clinician.
Contraindications
Avoid ketamine treatment if any of the following apply to you:
- Allergic to ketamine
- Symptoms of psychosis or mania
- Uncontrolled high blood pressure
- Congestive heart failure or other serious heart issues
- Severe respiratory issues
- History of elevated intraocular or intracranial pressure
- History of hyperthyroidism
- Other serious medical conditions
- Pregnant, nursing, or trying to become pregnant
Additional Risks
Ketamine may cause moderate psychological dependency in some users.
In rare cases, frequent, heavy users have reported issues such as frequent urination, incontinence, pain during urination, blood in the urine, or reduced bladder capacity.
Ketamine may also exacerbate issues in people with schizophrenia or severe personality disorders. Individuals with personal or family histories of psychosis should exercise caution with any psychoactive substances, including ketamine, and discuss risks with their clinician.
Safety Guidelines
Ketamine's dissociative effects can increase vulnerability and accident risk. For best outcomes and safety, follow these guidelines during treatment:
- Avoid operating vehicles or heavy machinery following treatment until after a full night's sleep.
- Do not take benzodiazepines or stimulants within 24 hours prior to treatment.
- Continue taking antihypertensive medications as prescribed.
- Do not take ketamine with alcohol or when hungover.
- Avoid solid foods within 3 hours and liquids within 1 hour of treatment.
Research and Effectiveness
A 2022 peer-reviewed study in the Journal of Affective Disorders titled "At-home, sublingual ketamine telehealth is a safe and effective treatment for moderate to severe anxiety and depression: Findings from a large, prospective, open-label effectiveness trial," showed promising results. The FDA has not conducted head-to-head trials comparing ketamine's safety to other FDA-approved medications for depression, anxiety, or psychiatric conditions. Some clients report better success with ketamine than with FDA-approved therapies, though these results may not be typical.
For more information about the informed consent clients can view and sign prior to treatment, please email us at support@mindscaperx.com.
Founder's Story
The Journey That Led To Mindscape
How It Works
Sign Up
Complete a short intake to register and book your virtual appointment.
Clinical Consultation
Meet with an independent provider to discuss your history and goals. If appropriate, they’ll create a personalized treatment plan.
Receive Your Medication
If approved, your prescribed medication will be shipped to your home by a partner pharmacy, typically within 5-6 business days.
Dynamic Support That Evolves With You
Standard treatments use a cookie-cutter approach. But your story is yours alone. Mindscape meets you where you are.
We coordinate with experienced providers who design individual treatment plans across a full dose range, from subtle microdoses to more immersive treatments. You and your provider will decide on the best way to take your medication: sublingual troches, nasal spray, or both.
As your path unfolds, your provider adjusts your plan as needed. Mindscape streamlines your clinical experience, supporting grounded and meaningful therapeutic sessions.
Mindscape works with independent providers who specialize in safe, effective ketamine therapy for individuals with depression, anxiety, and PTSD.
Experience Rapid Relief
Research shows that ketamine rapidly reduces depression and anxiety symptoms, often within 24 hours of treatment.
Improved Self-Connection
Ketamine therapy helps you access deep self-compassion and intuition, removing psychological barriers.
Fewer Side Effects
Ketamine typically has fewer side effects compared to traditional antidepressants.
Reduced Psychological Barriers
Ketamine can subdue the stress response in the nervous system, reducing feelings of fear.
Take It Anywhere, Anytime
You can use oral and nasal ketamine in the comfort of your home, on your own schedule.
Enhanced Creativity
By quieting self-doubt and removing mental barriers, ketamine frees the mind, allowing for heightened creativity.
Real Stories,
Real Science
Mid-range sublingual ketamine "produced rapid, clear and sustained effects, improving mood level and stability, cognition and sleep" in 77% of patients, according to a clinical study.
"Ketamine therapy gave me better access to myself, to things that had needed to be addressed for a long time. It enabled me to release the negative self-talk and embrace self compassion. Slowly, I developed a better relationship with myself, and now my whole game has changed."
Nearly 60% of patients with anxiety or depression experienced significant and persistent reduction in symptoms, according to a large-scale study. Based on their findings, the study authors concluded that "at-home sublingual ketamine therapy is an important avenue for overcoming long-standing barriers to depression and anxiety treatment, safely and conveniently."
Why choose
Ketamine therapy ?
Rapid mood support
Ketamine acts on glutamate, a neurotransmitter involved in learning and mood regulation. Because the glutamate system responds quickly, many people notice changes in mood and mental clarity within the first few sessions.
Build new neural pathways
Ketamine’s effect on glutamate is associated with increased neuroplasticity, or the formation of new neural connections. Neuroplasticity helps disrupt negative thought patterns, making it easier to develop healthier coping strategies. Over time, building new neural pathways may support lasting shifts in how you think, feel, and respond to stress.
Expand Your Current Treatment Options
Ketamine can complement certain antidepressants and other medications. During your consultation, you’ll review your current prescriptions with your provider to determine what’s appropriate for you.
Because of its unique mechanism in the brain, ketamine may offer an alternative to antidepressants for some people. A growing body of evidence suggests it may reduce depressive symptoms more rapidly than SSRIs, particularly in those who haven’t responded to other treatments.
Any changes to your current prescriptions should always be made in consultation with your prescribing provider.

